2010. 5. 5
Revised on 2011. 8. 16
Revised on 2012. 1. 25
Revised on 2013. 1. 30
Revised on 2015. 10. 26
Revised on 2017. 1. 31
Revised on 2018. 4. 1
Revised on 2019. 3. 22
Environmental Health and Toxicology (EHT) is an official journal of the Korean Society of Environmental Health and Toxicology (KOSEHT), and provides high quality of scientific information on environmental health and toxicology (ecotoxicology and risk assessment, environmental chemistry, human toxicology and risk assessment, environmental epidemiology, environmental exposure assessment, and other related areas) to encourage research, policy development and education on these fields. Contributions of original articles, systemic reviews, meeting or conference reports, brief reports, case reports, investigation reports, special topics, perspectives and commentaries, news and voices, column, editorials, letters to the editor and responses, and debates are welcome.
Scientific integrity: research and publication ethics
EHT follows the Guidelines on Good Publication (http://publicationethics.org) or Good Publication Practice Guidelines for Medical Journals of the Korean Association of Medical Journal Editors (http://kamje.or.kr). Authors must perform the research in accordance with principles of the Declaration of Helsinki (http://www.wma.net/en/30publications/10policies/b3/index.html).
1. Conflict of interest statement
Conflict of interest exists when an author (or the author’s institution), reviewer, or editor has financial or personal relationships that inappropriately influence (bias) his or her actions (such relationships are also known as dual commitments, competing interests, or competing loyalties). These relationships vary from being negligible to having great potential for influencing judgment. Not all relationships represent true conflict of interest. On the other hand, the potential for conflict of interest can exist regardless of whether an individual believes that the relationship affects his or her scientific judgment. Financial relationships (such as employment, consultancies, stock ownership, honoraria, and paid expert testimony) are the most easily identifiable conflicts of interest and the most likely to undermine the credibility of the journal, the authors, and of science itself. However, conflicts can occur for other reasons, such as personal relationships, academic competition, and intellectual passion (http://icmje.org/ethical_4conflicts.html). If there are any conflicts of interest, authors should disclose them in the manuscript. The conflicts of interest may occur during research process; however, important point is the disclosure itself. If there is a disclosure, editors, reviewers, and reader can approach the manuscripts after understanding the situation where the research work was processed.
2. Statement of human and animal rights, informed consent and institutional review board approval
Human research should be done in accordance of the Ethical Principles for Medical Research Involving Human Subjects, outlined in the Helsinki Declaration of 1975 (revised 2008), available from: http://www.wma.net/en/30publications/10policies/b3/. Clinical studies that do not meet the Helsinki Declaration will not be considered for publication. Human subjects should not be identifiable, such that patients’ names, initials, hospital numbers, dates of birth, or other protected healthcare information should not be disclosed. For animal subjects, research should be performed based on the National or Institutional Guide for the Care and Use of Laboratory Animals, and the ethical treatment of all experimental animals should be maintained. Copies of written informed consents should be kept for studies on human subjects. For the clinical and epidemiological studies of human subjects, there should be a certificate, agreement, or approval by the institutional review board (IRB). Approval and compliance with research requirements regarding human subjects must be noted, and information regarding informed consent procedures must be described in the “Methods” section of manuscripts concerning human subjects research. Authors should assure in the “Methods” section of manuscript that animals used in a study have been treated humanely and with regard for the alleviation of suffering, and that the protocol was approved by an institutional animal care and use committee.
3. Registration of the clinical trial research
Any research that deals with clinical trial should be registered to the primary national clinical trial registration site such as Korea Clinical Research Information Service (http://cris.nih.go.kr), other primary national registry sites accredited by World Health Organization (http://www.who.int/ictrp/network/primary/en/) or ClinicalTrials.gov (https://www.clinicaltrials.gov/), a service of the US National Institutes of Health.
Each author should have participated sufficiently in the work to take public responsibility for appropriate portions of the content and should meet the authorship criteria of the Uniform Requirement for Manuscripts Submitted to Biomedical Journals (http://icmje.org/ethical_1author.html). One or more authors should take responsibility for the integrity of the work as a whole, from inception to published article. Authorship credit should be based only on: 1) substantial contributions to conception and design, acquisition of data, or analysis and interpretation of data; 2) drafting the article or revising it critically for important intellectual content; 3) final approval of the version to be published; and 4) agreeing to be accountable for all aspects of the work in ensuring that the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved. Authors should meet these 4 conditions. If the number of authors is greater than 6, there should be a list of each author’s role for the submitted paper. If any persons who do not meet above 4 criteria, they may be placed as contributors in Acknowledgements section. The addition of an author to a manuscript under review is possible only with the editor’s approval. Changes in authorship cannot be made after the manuscript is accepted for publication. Multiple first authors can be accepted if corresponding author believes that the authors contributed equally while co-corresponding authors are not allowed.
5. Originality and duplicate publication
Contributions submitted to EHT must be original works of the author(s) and must not have been previously published in print or online or simultaneously submitted to another publication. The contents published as the proceedings or presentations in academic conference but not as the whole papers can be submitted to EHT. Authors should send related materials (published, in press or in reviewing) with the submitted manuscript to the editorial board. Any part of the accepted manuscript should not be duplicated in any other scientific journal without the permission of the editorial board, although the figures and tables can be used freely if original source is verified according to Creative Commons License. It is mandatory for all authors to resolve any copyright issues when citing a figure or table from a different journal that is not open access.
6. Secondary publication
It is possible to republish manuscripts if the manuscripts satisfy the condition of secondary publication of the Uniform Requirements for Manuscripts Submitted to Biomedical Journals by International Committee of Medical Journal Editors’, available from: http://www.icmje.org/publishing_4overlap.html as followings: Certain types of articles, such as guidelines produced by governmental agencies and professional organizations, may need to reach the widest possible audience. In such instances, editors sometimes deliberately publish material that is also being published in other journals, with the agreement of the authors and the editors of those journals. Secondary publication for various other reasons, in the same or another language, especially in other countries, is justifiable and can be beneficial provided that the following conditions are met. The authors have received approval from the editors of both journals (the editor concerned with secondary publication must have a photocopy, reprint, or manuscript of the primary version). The priority of
the primary publication is respected by a publication interval of at least one week (unless specifically negotiated otherwise by both editors). The paper for secondary publication is intended for a different group of readers; an abbreviated version could be sufficient. The secondary version faithfully reflects the data and interpretations of the primary version.
7. Process to manage the research and publication misconduct
When the Journal faces suspected cases of research and publication misconduct such as redundant (duplicate) publication, plagiarism, fabricated data, changes in authorship, undisclosed conflict of interest, ethical problem with a submitted manuscript, a reviewer who has appropriated an author’s idea or data, complaints against editors, and etc., the resolving process will be followed by flowchart provided by the Committee on Publication Ethics (http://publicationethics.org/resources/flowcharts). The discussion and decision on the suspected cases are done by editorial board.
Preparation of manuscript
Manuscripts written in English are accepted. Manuscripts should include a cover letter, title page, abstract, key words, manuscript body, acknowledgements, references, tables and figures in order. All part of the manuscript, except tables, must be double-spaced with A4 size of paper with a 12-pt size. Manuscript pages must be numbered consecutively, beginning with the title page, and the line numbers should be assigned in all pages. The text should be a single column format with 2.5 cm margins on the top, bottom, right and left.
1. Cover letter
You should supply an approximately one-page cover letter that:
2. Title page
The title page must include
- Specification of study design in the manuscript title is recommended. The first letter in the first word should be written with capital letters in manuscript title, authors’ name and affiliations. The abbreviations should not be used in the manuscript title. Title should not be over 15 words.
Abstracts should appear on a separate page and be no more than 300 words in length, and describe concisely, in a paragraph the objectives, methods, important results, and derived conclusions of the study are included in an unstructured format. For original articles, systemic reviews, meta-analysis, meeting or conference reports, brief reports, investigation reports, special topics, case reports, perspectives and hypothesis should provide an unstructured abstract. No abstract is required for editorials, letters to the editor and responses, news and voices, debates, and column. References should not be included in abstracts and abbreviations should be used sparingly.
4. Key words
Authors should provide a list of no more than six key words below the abstract
5. Manuscript body
The manuscript body should follow the requisites of each type of paper. A brief paragraph to clarify the main conclusion should be included at the end of the discussion section. In text, tables, and legends, identify references with Arabic numerals in square brackets, such as , , . Authors’ last names should be cited in English. For two authors, connect the names by “and.” For citations of three or more authors, include the first author’s last name followed by “et al.”
In between the manuscript body and reference lists, authors can describe acknowledgements and declare conflicts of interest.
Authors are responsible for the accuracy and completeness of references used in the manuscript. All references should be written in English. References written in other languages are indicated by writing (Korean, Japanese, Chinese, etc.) at the end. References should be numbered sequentially and cited in their order of use in the main body of the manuscript. References should be cited according to the system in the Index Medicus used by the American National Library of Medicine as shown in the following examples. Those not shown in the examples should be cited according to “Uniform Requirements for Manuscripts Submitted to Biomedical Journals” (http://www.icmje.org). Avoid using “abstracts,” “unpublished observations” and “personal communications” as references.
<Article within a journal>
For six or fewer authors, list the surnames and initials of all authors; for seven or more list the first six authors and add et al., title of article, name of journal abbreviated according to Index Medicus style, year, volume, issue, first and last page numbers.
Kwon JH, Katz LE, Liljestr and HM. Use of a parallel artificial membrane system to evaluate passive absorption and elimination in small fish. Environ Toxicol Chem 2006;25(12):3083-3092.Kim HH, Yang JY, Kim SD, Yang SH, Lee CS, Shin DC, et al. Health risks assessment in children for phthalate exposure associated with childcare facilities and indoor playgrounds. Environ Health Toxicol 2011;26:e2011008.
Landis WG, Sofield RM, Yu MH. Introduction to environmental toxicology: molecular substructures to ecological landscapes. 4th ed. Boca Raton: CRC Press; 2011, p. 13-33.
<Chapter in books>
Künzli N, Perez L. Health risk assessment. In: Baker DB, Nieuwenhuijsen MJ, editors. Environmental epidemiology: study methods and application. Oxford: Oxford University Press; 2008, p. 319- 348.
<Data found on the Internet>
International Agency for Research on Cancer. Agents classified by the IARC monographs, volumes 1-102. IARC monographs on the evaluation of carcinogenic risks to humans [cited 2012 Feb 6]. Available from: http://monographs.iarc.fr/ENG/ Classification/ClassificationsGroupOrder.pdf.
Kim YS. Association between heavy metal exposure and dental caries in children [dissertation]. Cheonan: Dankook University;2011 (Korean).
8. Tables and figures
The use of tables, figures, and photographs that supplement the text are recommended but should not duplicate material found in the body of the manuscript. Tables and figures should be presented in English and prepared with separate files. Approximate locations should be marked in the manuscript body. Titles for tables and figures should be self-explanatory with the first word written with an upper case letter and the rest in lower case letters. The same principle is applied to the content of a table or figure. Tables are prepared with no horizontal or vertical dividing lines. Each table and figure should be presented in a separate page and do not exceed one page for each as possible. If the table covers more than one page, note “(continued)” at the end of title of the successive tables. Explanations for and abbreviations used in tables and figures are included as footnotes. Footnotes are indicated by superscript numbers in alphabetical order (a,b,c,...). All numbers should be expressed to 2 digits to the right of the decimal points after rounding, otherwise specified. A p-value may be indicated as follows in the footnotes:+p<0.1, *p<0.05, **p<0.01, ***p<0.001.
All non-standard abbreviations (organochlorine [OC] pesticides, limit of detection [LOD], polymerase chain reaction [PCR]) and chemical compounds (e.g., polychlorinated biphenyls, PCBs; carbon dioxide, CO2) should be defined in the text on first use and abbreviated thereafter. Do not use non-standard unit of measure as possible. The names of chemical compounds should be met the rule of nomenclature of the International Union of Pure and Applied Chemistry (IUPAC). Use generic name rather than brand name unless the brand name itself is important for the study purposes. Use Arabic number for all numbers, small p for probability, % for percentage, meter for length, ˚C for temperature, mmHg for blood pressure, and g/dL for hemoglobin. Follow the methods (meter, kilogram, liter) of the International System of Units (SI units), otherwise specified. Let a space in between the measured number and unit.
10. Language and style
EHT T can only publish manuscript written in English. Spelling should be US English or British English, but not a mixture. Gene names should be in italic, but protein products should be in plain type. Editorial board can help authors of on-native speakers of English to make use of a copyediting service. EHT follows the NLM style guide for authors, otherwise specified (Patrias, K. Citing medicine: the NLM style guide for authors, editors, and publishers [Internet]. 2nd ed. Wendling, DL, technical editor. Bethesda (MD): National Library of Medicine (US); 2007 [updated 2009 Jan 14; 2008 Apr 14]. Available from: http://www. nlm.nih.gov/citingmedicine).
11. Others: a note on reporting guidelines
Authors are encouraged to follow the specific guidelines according to their relevant design and research methods:
- We encourage the use of the Sex and Gender Equity in Research (SAGER) guidelines for reporting of sex and gender information in study design, data analyses, results and interpretation. This includes the correct use of the terms sex (when reporting biological factors) and gender (when reporting identity, psychosocial, or cultural factors) and, unless inappropriate, reporting the sex and/or gender of study participants, the sex of animals or cells, and description of the methods used to determine sex and gender. If the study was done involving an exclusive population, for example in only one sex, authors should justify why, except in obvious cases (e.g., prostate cancer). Authors should define how they determined race or ethnicity and justify their relevance.
12. ORCID (Open Researcher and Contributor ID)
ORCID of all authors are recommended to be provided. To have ORCID, authors should register in the ORCID web site available from: https://orcid.org/. Registration is free to every researchers in the world.
Type of manuscript
- Original articles present scientific research and discovery in the field of environmental health and toxicology. The main text must follow the standard EHT format, with Introduction and separate sections for Methods, Results and Discussion.
- Systemic reviews provide an overview, integration of information, and critical analysis of a particular field of research or theme related to environmental health sciences. Previous research should be comprehensively reviewed regardless of whether the findings are consistent with expectations or the review authors’ hypotheses. It is appropriate for authors to discuss the strengths and weaknesses of individual studies, focus on high-quality studies that add to the weight of the evidence on the topic under review, identify information gaps, and make recommendations for future research.
- Meta-analyses present, contrast, or combine data across studies to address a specific study question related to environmental health and toxicology. Inclusion criteria and strategies used to search the literature should be explicitly described, along with analytic methods used to evaluate or combine data. The potential for publication bias and heterogeneity among studies should be investigated, and graphical displays of data contributed by individual studies are encouraged. The strengths and weaknesses of individual studies and potential causes of discordant findings among studies also should be discussed. Authors should integrate and critically analyze information from previous research, identify information gaps, and make recommendations for future research.
- Meeting or Conference reports are intended to provide an overview of outcomes of conferences, symposia, or workshops. Authors should submit reports that review the state of the science for a particular area, identify research gaps and needs, and explain how the outcome of the conference addresses those gaps and needs. De novo data, participant lists, dialogue of workgroups or committees, and discussion of the internal organization of the meeting are not allowed. Meeting reports must be submitted to EHT no later than 1 year after the events they describe. Prospective authors should consult with the editor-in-chief before submitting a Meeting report. The word limit of text is 5,000, with up to 50 references.
- Brief reports are short reports of original studies or evaluations.
- Case reports present case presentations of patients with a direct or indirect link of relevance to environmental exposures and environmental health. Visual images or other graphics are encouraged.
- Investigation reports are epidemiological investigation reports on community health effects or outbreak in relation with environmental exposure or event. Brief description of the exposure circumstances, methods and results of the epidemiological investigation should be presented.
- Special topics (including practice of environmental health and toxicology) are can be made by the decision of editorial boards which invite authors to write manuscripts
- Perspectives (including commentaries) present a forum for raising awareness to timely environmental health and toxicological issues. It provides an opportunity for authors to offer their critical evaluation of recent trends and advances in environmental health and toxicology.
- Editorials are short presentation on any issue related to environmental health and toxicology and EHT by the editorial boards or authors requested by the editorial boards. Editorials do not undergo peer review.
- Letters to the editor and Responses should address specific scientific issues or questions raised by the article published. Authors cited in the Letters may be given the opportunity to respond. It may include a brief table or small figure if it is critical to the discussion.
- Debates will serve as a forum for discussing controversy and critical issues in environmental health and toxicology. Typically, two articles address a controversial topic presenting different or opposing viewpoints. The editorial member will commission the articles for debate, but authors are welcome to suggest potential topics of interest and to inquire about possible submission.
- Hypothesis is as theoretical paper that presents a radical, speculative and non-mainstream scientific idea and should be an organized logical structure or model. It accounts some known facts and has real world consequences that are (in principle) observable.
- News and Voices are as scientific essay on the environmental science and policy issues, including comments, opinions, book reviews, obituaries of distinguished scholar in environmental health and toxicology, and other free-style article.
- Column is a personal essay in the environmental health and toxicology field. The manuscript for column is invited by the editor-in-chief.
The maximum number of words in abstract, main body, references, and tables and figures were shown in the Table 1.
- Table 1. Recommended maximum word counts, number of references, tables, and figures by article type
Submission of manuscript
Submission of manuscript should be made via the EHT’s submission web site (http://submit.e-eht.org/). Manuscripts can be submitted at any time. Original source files (MS Word) are requires for submission; PDF files will not be accepted.
Upon submission of a manuscript, the editorial board for the EHT will review the paper for appropriateness of content. Articles can be rejected at this initial review process. Articles are reviewed by two or three experts with anonymity in the field. Peer review averages two months to complete. The editorial boards reserve the right to edit a manuscript for phrasing, style, and overall length at any stage prior to publication, while maintaining the scientific accuracy of the manuscript. Based on comments from reviewers and editors, authors may be asked to revise their manuscript. Authors are required to submit a letter of explanation regarding how they dealt with all comments and questions raised by reviewers and editors. If revisions cannot be submitted within two months, author(s) may request one month grace period. Manuscripts will not be returned after submission.
Upon acceptance for publication, one file of the final files should be submitted to the web site (http://submit.e-eht.org/). Dates of submission and acceptance appear in the journal’s website. The accepted manuscripts immediately appear as epub ahead of print in the PubMed (http://www.ncbi.nlm.nih.gov/pubmed/).
Page proofs will be transmitted to corresponding authors by email as PDF files. Authors are responsible for the content of page proofs. All page proofs should be read carefully, corrected if necessary, and returned within 48 hours of receipt. Corrections should be restricted to typesetting errors. Changes or additions to the edited manuscript are not allowed at this stage. Authors are responsible for the final contents of the printed manuscript.
The Korean Society of Environmental Toxicology and Health owns all copyrights of manuscripts published in EHT. Authors will be asked to sign the journal’s “Authorship Responsibility and Copyright Transfer” form. This form will be sent to the corresponding author via e-mail upon acceptance of a manuscript. The corresponding author is responsible for obtaining signatures of all authors consenting to copyright transfer. The author is responsible for the content of both the original and reviewed and edited manuscript, accuracy of references and quotes, and for any violations of the copyright agreement. After the manuscript is accepted for publication, it will not be published elsewhere, in any other language, without the written consent of the copyright-holder.
EHT requests no page charges for accepted manuscripts.
In case of finding error typing, authors should send table of errors correction in a month to the editorial board that will be published at the following issue.
Supplemental figures, movie legends, tables, experimental procedures, and references should be provided as a single Word file that contains all supplemental materials. All supplemental materials should be referred in the appropriate places of the manuscript text.
Author’s checklist items before submission
Please be sure to check over items from No.1 to No. 12.